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DTB commentary
What does the TIME study tell us about morning and evening dosing of antihypertensive medication?
  1. Teck K Khong12,
  2. George S Lin3
  1. 1 Clinical Pharmacology, St George's University of London, London, UK
  2. 2 Blood Pressure Unit, St George's Hospital, London, UK
  3. 3 St George's University of London, London, UK
  1. Correspondence to Dr Teck K Khong, Clinical Pharmacology, St George's University of London, London SW17 0RE, UK; tkhong{at}sgul.ac.uk

Abstract

Commentary on: Mackenzie IS, Rogers A, Poulter NR, et al. Cardiovascular outcomes in adults with hypertension with evening vs morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial. Lancet. 2022;400:1417–25.

  • Drug-Related Side Effects and Adverse Reactions
  • Health Care Quality, Access, and Evaluation

https://doi.org/10.1136/dtb.2023.000002

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    Footnotes

    • Series co-ordinator Dr Teck Khong, DTB Associate Editor, Clinical Pharmacology, St George’s, University of London, UK

    • Competing interests None declared. Refer to the online supplementary files to view the ICMJE form(s).

    • Provenance and peer review Commissioned; internally peer reviewed.

    • Supplemental material This content has been supplied by the author(s). It has not been vetted by BMJ Publishing Group Limited (BMJ) and may not have been peer-reviewed. Any opinions or recommendations discussed are solely those of the author(s) and are not endorsed by BMJ. BMJ disclaims all liability and responsibility arising from any reliance placed on the content. Where the content includes any translated material, BMJ does not warrant the accuracy and reliability of the translations (including but not limited to local regulations, clinical guidelines, terminology, drug names and drug dosages), and is not responsible for any error and/or omissions arising from translation and adaptation or otherwise.